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Dihydroorotate dehydrogenase (DHODH) inhibitor

Showing 1 - 25 of 7,572
STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED

Leukemia Trial in France, United States (BAY2402234)

Terminated
  • Leukemia
  • Bronx, New York
  • +4 more
Dec 20, 2021

Acute Myeloid Leukemia, MDS, Chronic Myelomonocytic Leukemia Trial in Worldwide (JNJ-74856665, AZA, VEN)

Active, not recruiting
  • Acute Myeloid Leukemia
  • +2 more
  • Birmingham, Alabama
  • +22 more
Jan 27, 2023

Primary Sclerosing Cholangitis Trial in Phoenix, Tempe, Rochester (Vidofludimus calcium)

Completed
Has Results
  • Primary Sclerosing Cholangitis
  • Vidofludimus calcium
  • Phoenix, Arizona
  • +2 more
Oct 11, 2022

MDS, Chronic Myelomonocytic Leukemia, Acute Myeloid Leukemia Trial (RP7214)

Not yet recruiting
  • Myelodysplastic Syndromes
  • +2 more
  • (no location specified)
Aug 17, 2022

Leukemia, Myeloid, Acute, AML Trial in United States (PTC299)

Terminated
  • Leukemia, Myeloid, Acute
  • AML
  • Aurora, Colorado
  • +16 more
Jan 18, 2022

COVID-19 Trial in Chertsey (leflunomide)

Active, not recruiting
  • COVID-19
  • Chertsey, United Kingdom
    Ashford and St Peters Hospital NHS Foundation Trust
Aug 12, 2021

MEN1 Gene Mutation Trial in Basel (Leflunomide 20 mg)

Not yet recruiting
  • MEN1 Gene Mutation
  • Leflunomide 20 mg
  • Basel, Switzerland
    Unispital Basel
Nov 1, 2022

COVID-19 Infection Trial in United States (Brequinar, Placebo)

Completed
Has Results
  • COVID-19 Infection
  • Homewood, Alabama
  • +13 more
Apr 14, 2022

Keratoconjunctivitis Trial in Vienna (PP-001, Placebo)

Unknown status
  • Keratoconjunctivitis
  • Vienna, Austria
    University Hospital Vienna
Mar 10, 2020

Lymphoma Trial in United States (AG-636)

Terminated
  • Lymphoma
  • New Haven, Connecticut
  • +5 more
Aug 21, 2020

Non-infectious Uveitis Trial in Worldwide (PP-001)

Unknown status
  • Non-infectious Uveitis
  • Vienna, Austria
  • +8 more
Mar 10, 2020

Mechanistic Studies of Teriflunomide in RRMS

Active, not recruiting
  • Relapsing Remitting Multiple Sclerosis
  • Ann Arbor, Michigan
    University of Michigan
Jul 27, 2022

Relapsing-Remitting Multiple Sclerosis (RRMS) Trial in Worldwide (IMU-838 (30 mg/day), IMU-838 (45 mg/day), Placebo)

Active, not recruiting
Has Results
  • Relapsing-Remitting Multiple Sclerosis (RRMS)
  • IMU-838 (30 mg/day)
  • +3 more
  • Blagoevgrad, Bulgaria
  • +37 more
Jan 19, 2022

Melanoma (Skin), Skin Cancer, Skin Melanoma Trial in Tampa (Vemurafenib, Cobimetinib)

Recruiting
  • Melanoma (Skin)
  • +3 more
  • Tampa, Florida
    H. Lee Moffitt Cancer Center and Research Institute
Dec 30, 2022

Advanced Solid Tumor, Platinum-Resistant Ovarian Cancer, Platinum-Resistant Urothelial Carcinoma Trial in Darlinghurst, Kogarah,

Terminated
  • Advanced Solid Tumor
  • +3 more
  • Darlinghurst, New South Wales, Australia
  • +1 more
Dec 18, 2022

Adult Gliomas, Mixed Trial in San Francisco (Hyperpolarized Carbon 13 Alpha-ketoglutarate (HP C13-aKG), Magnetic Resonance Image

Recruiting
  • Adult Gliomas, Mixed
  • Hyperpolarized Carbon 13 Alpha-ketoglutarate (HP C13-aKG)
  • Magnetic Resonance Image (MRI)
  • San Francisco, California
    University of California, San Francisco
May 9, 2023

MDS, Acute Myeloid Leukemia Trial in New Haven (AG-120, Nivolumab)

Withdrawn
  • Myelodysplastic Syndromes
  • Acute Myeloid Leukemia
  • New Haven, Connecticut
    Yale Cancer Center
Jan 6, 2022

Recurrent Acute Myeloid Leukemia Trial in Duarte (Bosutinib Monohydrate, Decitabine, Enasidenib Mesylate)

Withdrawn
  • Recurrent Acute Myeloid Leukemia
  • Bosutinib Monohydrate
  • +6 more
  • Duarte, California
    City of Hope Meidcal Center
Jun 7, 2022

Type 2 Diabetes in Obese, Obesity, Type2Diabetes Trial in San Diego (SPI-62, Cortisone-d8)

Completed
  • Type 2 Diabetes Mellitus in Obese
  • +2 more
  • Chula Vista, California
    ProSciento
Jan 26, 2023

Astrocytoma Trial (Vorasidenib, Pembrolizumab)

Not yet recruiting
  • Astrocytoma
  • (no location specified)
Aug 1, 2022

Melanoma Trial in Beijing (tunlametinib, paclitaxel +carboplatin, or temozolomide +cisplatin, or dacarbazine +cisplatin)

Not yet recruiting
  • Melanoma
  • tunlametinib
  • paclitaxel +carboplatin, or temozolomide +cisplatin, or dacarbazine +cisplatin
  • Beijing, Beijing, China
    Beijing Cancer Hospital
Aug 15, 2023

SARS-CoV-2 Infection Trial in India (RP7214 + Standard of care (SOC), Placebo + Standard of care (SOC))

Completed
  • SARS-CoV-2 Infection
  • RP7214 + Standard of care (SOC)
  • Placebo + Standard of care (SOC)
  • Bangalore, India
  • +15 more
Apr 20, 2022

Medium-chain Acyl-CoA Dehydrogenase Deficiency Trial in Pittsburgh (Triheptanoin)

Recruiting
  • Medium-chain Acyl-CoA Dehydrogenase Deficiency
  • Pittsburgh, Pennsylvania
    UPMC Children's Hospital of Pittsburgh
Sep 27, 2023

IDH Mutation, IDH1 Mutation, IDH2 Gene Mutation Trial in Chicago (Ivosidenib, Enasidenib, Fedratinib)

Recruiting
  • IDH Mutation
  • +4 more
  • Chicago, Illinois
    University of Chicago Medical Center
Nov 12, 2021

Lactate Blood Increase, Thiamine Deficiency Trial in Charleroi (Thiamine 500 MG, Placebo)

Completed
  • Lactate Blood Increase
  • Thiamine Deficiency
  • Thiamine 500 MG
  • Placebo
  • Charleroi, Hainaut, Belgium
    CHU-Charleroi Hopital Civil Marie Curie
Nov 16, 2022